About MARVEL domain-containing protein 1
MARVEL domain-containing protein 1 (MARVELD1) is a protein
from Homo sapiens identified by UniProt accession
Q9BSK0, 173 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | MARVEL domain-containing protein 1 |
|---|
| UniProt accession | Q9BSK0 |
|---|
| Gene | MARVELD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 173 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- risky sexual behaviour measurement · score 0.13
- alcohol dependence · score 0.13
- cancer · score 0.08
- neoplasm · score 0.05
- Dysequilibrium syndrome · score 0.04
- spinocerebellar ataxia type 29 · score 0.04
- microcephalic primordial dwarfism due to ZNF335 deficiency · score 0.04
- mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations · score 0.04
- spinocerebellar ataxia type 27 · score 0.04
- lissencephaly due to TUBA1A mutation · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BSK0-F1 | alphafold | PREDICTED | 85.26 | — |
Amino-acid sequence (173 residues)
MLPPPPRQPP PQARAARGAV RLQRPFLRSP LGVLRLLQLL AGAAFWITIA TSKYQGPVHF ALFVSVLFWL LTLGLYFLTL LGKHELVPVL GSRWLMVNVA HDVLAAALYG AATGIMSDQM QRHSYCNLKD YPLPCAYHAF LAAAVCGGVC HGLYLLSALY GCGRRCQGKQ EVA
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