About Transmembrane protein 204
Transmembrane protein 204 (TMEM204) is a protein
from Homo sapiens identified by UniProt accession
Q9BSN7, 226 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Transmembrane protein 204 |
|---|
| UniProt accession | Q9BSN7 |
|---|
| Gene | TMEM204 |
|---|
| Organism | Homo sapiens |
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| Length | 226 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- appendicular lean mass · score 0.19
- Inguinal hernia · score 0.12
- short-rib thoracic dysplasia 9 with or without polydactyly · score 0.12
- platelet count · score 0.12
- coronary artery disease · score 0.09
- snoring measurement · score 0.08
- mean corpuscular hemoglobin concentration · score 0.07
- body height · score 0.05
- lung adenocarcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BSN7-F1 | alphafold | PREDICTED | 71.06 | — |
Amino-acid sequence (226 residues)
MTVQRLVAAA VLVALVSLIL NNVAAFTSNW VCQTLEDGRR RSVGLWRSCW LVDRTRGGPS PGARAGQVDA HDCEALGWGS EAAGFQESRG TVKLQFDMMR ACNLVATAAL TAGQLTFLLG LVGLPLLSPD APCWEEAMAA AFQLASFVLV IGLVTFYRIG PYTNLSWSCY LNIGACLLAT LAAAMLIWNI LHKREDCMAP RVIVISRSLT ARFRRGLDND YVESPC
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