LIM domain-containing protein 2 (LIMD2)

About LIM domain-containing protein 2

LIM domain-containing protein 2 (LIMD2) is a protein from Homo sapiens identified by UniProt accession Q9BT23, 127 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.

Target properties

Protein name	LIM domain-containing protein 2
UniProt accession	Q9BT23
Gene	LIMD2
Organism	Homo sapiens
Length	127 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (58)

Diseases linked to this target (Open Targets).

body mass index · score 0.28
body height · score 0.28
waist-hip ratio · score 0.24
body fat percentage · score 0.24
BMI-adjusted hip circumference · score 0.23
leukocyte count · score 0.19
vital capacity · score 0.19
lifestyle measurement · score 0.17
mean corpuscular volume · score 0.16
forced expiratory volume · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BT23-F1	alphafold	PREDICTED	72.16	—

Amino-acid sequence (127 residues)

MFQAAGAAQA TPSHDAKGGG SSTVQRSKSF SLRAQVKETC AACQKTVYPM ERLVADKLIF HNSCFCCKHC HTKLSLGSYA ALHGEFYCKP HFQQLFKSKG NYDEGFGRKQ HKELWAHKEV DPGTKTA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards