Proteasome assembly chaperone 3 (PSMG3)

About Proteasome assembly chaperone 3

Proteasome assembly chaperone 3 (PSMG3) is a protein from Homo sapiens identified by UniProt accession Q9BT73, 122 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Proteasome assembly chaperone 3
UniProt accession	Q9BT73
Gene	PSMG3
Organism	Homo sapiens
Length	122 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
urate measurement · score 0.21
bone density · score 0.21
serum gamma-glutamyl transferase measurement · score 0.13
blood protein measurement · score 0.09
glioblastoma multiforme · score 0.08
hepatocellular carcinoma · score 0.08
age at menarche · score 0.07
lung adenocarcinoma · score 0.06
body height · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BT73-F1	alphafold	PREDICTED	92.92	—

Amino-acid sequence (122 residues)

MEDTPLVISK QKTEVVCGVP TQVVCTAFSS HILVVVTQFG KMGTLVSLEP SSVASDVSKP VLTTKVLLGQ DEPLIHVFAK NLVAFVSQEA GNRAVLLAVA VKDKSMEGLK ALREVIRVCQ VW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards