About Protein ABHD14A
Protein ABHD14A (ABHD14A) is a protein
from Homo sapiens identified by UniProt accession
Q9BUJ0, 271 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Protein ABHD14A |
|---|
| UniProt accession | Q9BUJ0 |
|---|
| Gene | ABHD14A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 271 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.18
- MODY · score 0.08
- age at first birth measurement · score 0.07
- diabetes mellitus, transient neonatal, 2 · score 0.05
- hyperlipoproteinemia type V · score 0.05
- Hyperlipoproteinemia type 5 · score 0.05
- cholesterol-ester transfer protein deficiency · score 0.04
- hypertriglyceridemia 2 · score 0.04
- Hyperlipoproteinemia type 4 · score 0.03
- pancreatic triacylglycerol lipase deficiency · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BUJ0-F1 | alphafold | PREDICTED | 86.18 | — |
Amino-acid sequence (271 residues)
MVGALCGCWF RLGGARPLIP LGPTVVQTSM SRSQVALLGL SLLLMLLLYV GLPGPPEQTS CLWGDPNVTV LAGLTPGNSP IFYREVLPLN QAHRVEVVLL HGKAFNSHTW EQLGTLQLLS QRGYRAVALD LPGFGNSAPS KEASTEAGRA ALLERALRDL EVQNAVLVSP SLSGHYALPF LMRGHHQLHG FVPIAPTSTQ NYTQEQFWAV KTPTLILYGE LDHILARESL RQLRHLPNHS VVKLRNAGHA CYLHKPQDFH LVLLAFLDHL P
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