About Sodium channel modifier 1
Sodium channel modifier 1 (SCNM1) is a protein
from Homo sapiens identified by UniProt accession
Q9BWG6, 230 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Sodium channel modifier 1 |
| UniProt accession | Q9BWG6 |
| Gene | SCNM1 |
| Organism | Homo sapiens |
| Length | 230 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.16
- lymphocyte count · score 0.05
- non-melanoma skin carcinoma · score 0.04
- skin cancer · score 0.04
- skin carcinoma · score 0.03
- orofaciodigital syndrome · score 0.01
- systemic juvenile idiopathic arthritis · score 0.01
- Epileptic encephalopathy · score 0.00
- Dystonia · score 0.00
- nervous system disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9BWG6-F1 | alphafold | PREDICTED | 69.68 | — |
Amino-acid sequence (230 residues)
MSFKREGDDW SQLNVLKKRR VGDLLASYIP EDEALMLRDG RFACAICPHR PVLDTLAMLT AHRAGKKHLS SLQLFYGKKQ PGKERKQNPK HQNELRREET KAEAPLLTQT RLITQSALHR APHYNSCCRR KYRPEAPGPS VSLSPMPPSE VKLQSGKISR EPEPAAGPQA EESATVSAPA PMSPTRRRAL DHYLTLRSSG WIPDGRGRWV KDENVEFDSD EEEPPDLPLD
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