About Cell cycle regulator of non-homologous end joining
Cell cycle regulator of non-homologous end joining (CYREN) is a protein
from Homo sapiens identified by UniProt accession
Q9BWK5, 157 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Cell cycle regulator of non-homologous end joining |
|---|
| UniProt accession | Q9BWK5 |
|---|
| Gene | CYREN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 157 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.28
- monocyte count · score 0.18
- cytokine measurement · score 0.15
- response to vaccine · score 0.15
- serum alanine aminotransferase measurement · score 0.10
- alkaline phosphatase measurement · score 0.09
- monocyte percentage of leukocytes · score 0.09
- high density lipoprotein cholesterol measurement · score 0.08
- apolipoprotein A 1 measurement · score 0.08
- aspartate aminotransferase measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWK5-F1 | alphafold | PREDICTED | 65.69 | — |
Amino-acid sequence (157 residues)
METLQSETKT RVLPSWLTAQ VATKNVAPMK APKRMRMAAV PVAAARLPAT RTVYCMNEAE IVDVALGILI ESRKQEKACE QPALAGADNP EHSPPCSVSP HTSSGSSSEE EDSGKQALAP GLSPSQRPGG SSSACSRSPE EEEEEDVLKY VREIFFS
Explore Cell cycle regulator of non-homologous end joining with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets