About Adenosine 5'-monophosphoramidase HINT2
Adenosine 5'-monophosphoramidase HINT2 (HINT2) is a protein
from Homo sapiens identified by UniProt accession
Q9BX68, 163 residues long.
MolForge cross-references it against 0 known binders and
96 disease associations.
Target properties
| Protein name | Adenosine 5'-monophosphoramidase HINT2 |
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| UniProt accession | Q9BX68 |
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| Gene | HINT2 |
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| Organism | Homo sapiens |
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| Length | 163 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (96)
Diseases linked to this target (Open Targets).
- colorectal carcinoma · score 0.07
- neoplasm · score 0.06
- hepatocellular carcinoma · score 0.06
- CIDEC-related familial partial lipodystrophy · score 0.05
- myocardial infarction · score 0.05
- Ocular Melanoma · score 0.05
- LIPE-related familial partial lipodystrophy · score 0.05
- glycogen storage disease VI · score 0.05
- PLIN1-related familial partial lipodystrophy · score 0.05
- neonatal intrahepatic cholestasis due to citrin deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BX68-F1 | alphafold | PREDICTED | 83.85 | — |
Amino-acid sequence (163 residues)
MAAAVVLAAG LRAARRAVAA TGVRGGQVRG AAGVTDGNEV AKAQQATPGG AAPTIFSRIL DKSLPADILY EDQQCLVFRD VAPQAPVHFL VIPKKPIPRI SQAEEEDQQL LGHLLLVAKQ TAKAEGLGDG YRLVINDGKL GAQSVYHLHI HVLGGRQLQW PPG
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