About Zinc finger protein 471
Zinc finger protein 471 (ZNF471) is a protein
from Homo sapiens identified by UniProt accession
Q9BX82, 626 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Zinc finger protein 471 |
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| UniProt accession | Q9BX82 |
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| Gene | ZNF471 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 626 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- body height · score 0.32
- neurodegenerative disease · score 0.32
- alkaline phosphatase measurement · score 0.28
- lymphocyte count · score 0.25
- antisocial behaviour measurement · score 0.25
- attention deficit hyperactivity disorder · score 0.25
- substance abuse · score 0.25
- low density lipoprotein cholesterol measurement · score 0.25
- apolipoprotein B measurement · score 0.23
- neoplasm · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BX82-F1 | alphafold | PREDICTED | 72.84 | — |
Amino-acid sequence (626 residues)
MNVEVVKVMP QDLVTFKDVA IDFSQEEWQW MNPAQKRLYR SMMLENYQSL VSLGLCISKP YVISLLEQGR EPWEMTSEMT RSPFSDWESI YVTQELPLKQ FMYDDACMEG ITSYGLECST FEENWKWEDL FEKQMGSHEM FSKKEIITHK ETITKETEFK YTKFGKCIHL ENIEESIYNH TSDKKSFSKN SMVIKHKKVY VGKKLFKCNE CDKTFTHSSS LTVHFRIHTG EKPYACEECG KAFKQRQHLA QHHRTHTGEK LFECKECRKA FKQSEHLIQH QRIHTGEKPY KCKECRKAFR QPAHLAQHQR IHTGEKPYEC KECGKAFSDG SSFARHQRCH TGKRPYECIE CGKAFRYNTS FIRHWRSYHT GEKPFNCIDC GKAFSVHIGL ILHRRIHTGE KPYKCGVCGK TFSSGSSRTV HQRIHTGEKP YECDICGKDF SHHASLTQHQ RVHSGEKPYE CKECGKAFRQ NVHLVSHLRI HTGEKPYECK ECGKAFRISS QLATHQRIHT GEKPYECIEC GNAFKQRSHL AQHQKTHTGE KPYECNECGK AFSQTSNLTQ HQRIHTGEKP YKCTECGKAF SDSSSCAQHQ RLHTGQRPYQ CFECGKAFRR KLSLICHQRS HTGEEP
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