G-protein coupled receptor 87 (GPR87)

About G-protein coupled receptor 87

G-protein coupled receptor 87 (GPR87) is a protein from Homo sapiens identified by UniProt accession Q9BY21, 358 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.

Target properties

Protein name	G-protein coupled receptor 87
UniProt accession	Q9BY21
Gene	GPR87
Organism	Homo sapiens
Length	358 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (107)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.34
lymphocyte count · score 0.24
leukocyte count · score 0.20
diverticular disease · score 0.18
mean platelet volume · score 0.17
diverticulitis · score 0.10
hypertension · score 0.09
neoplasm · score 0.09
platelet-to-lymphocyte ratio · score 0.09
lung adenocarcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BY21-F1	alphafold	PREDICTED	81.88	—

Amino-acid sequence (358 residues)

MGFNLTLAKL PNNELHGQES HNSGNRSDGP GKNTTLHNEF DTIVLPVLYL IIFVASILLN GLAVWIFFHI RNKTSFIFYL KNIVVADLIM TLTFPFRIVH DAGFGPWYFK FILCRYTSVL FYANMYTSIV FLGLISIDRY LKVVKPFGDS RMYSITFTKV LSVCVWVIMA VLSLPNIILT NGQPTEDNIH DCSKLKSPLG VKWHTAVTYV NSCLFVAVLV ILIGCYIAIS RYIHKSSRQF ISQSSRKRKH NQSIRVVVAV FFTCFLPYHL CRIPFTFSHL DRLLDESAQK ILYYCKEITL FLSACNVCLD PIIYFFMCRS FSRRLFKKSN IRTRSESIRS LQSVRRSEVR IYYDYTDV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards