About Solute carrier family 2, facilitated glucose transporter member 11
Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11) is a protein
from Homo sapiens identified by UniProt accession
Q9BYW1, 496 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 11 |
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| UniProt accession | Q9BYW1 |
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| Gene | SLC2A11 |
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| Organism | Homo sapiens |
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| Length | 496 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.29
- sleep duration · score 0.29
- neurodegenerative disease · score 0.18
- serum gamma-glutamyl transferase measurement · score 0.18
- sex hormone-binding globulin measurement · score 0.09
- neutrophil count · score 0.08
- leukocyte count · score 0.07
- IGF-1 measurement · score 0.04
- lung adenocarcinoma · score 0.04
- macrophage migration inhibitory factor measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYW1-F1 | alphafold | PREDICTED | 88.46 | — |
Amino-acid sequence (496 residues)
MRALRRLIQG RILLLTICAA GIGGTFQFGY NLSIINAPTL HIQEFTNETW QARTGEPLPD HLVLLMWSLI VSLYPLGGLF GALLAGPLAI TLGRKKSLLV NNIFVVSAAI LFGFSRKAGS FEMIMLGRLL VGVNAGVSMN IQPMYLGESA PKELRGAVAM SSAIFTALGI VMGQVVGLRE LLGGPQAWPL LLASCLVPGA LQLASLPLLP ESPRYLLIDC GDTEACLAAL RRLRGSGDLA GELEELEEER AACQGCRARR PWELFQHRAL RRQVTSLVVL GSAMELCGND SVYAYASSVF RKAGVPEAKI QYAIIGTGSC ELLTAVVSCV VIERVGRRVL LIGGYSLMTC WGSIFTVALC LQSSFPWTLY LAMACIFAFI LSFGIGPAGV TGILATELFD QMARPAACMV CGALMWIMLI LVGLGFPFIM EALSHFLYVP FLGVCVCGAI YTGLFLPETK GKTFQEISKE LHRLNFPRRA QGPTWRSLEV IQSTEL
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