Large ribosomal subunit protein mL37 (MRPL37)

About Large ribosomal subunit protein mL37

Large ribosomal subunit protein mL37 (MRPL37) is a protein from Homo sapiens identified by UniProt accession Q9BZE1, 423 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Large ribosomal subunit protein mL37
UniProt accession	Q9BZE1
Gene	MRPL37
Organism	Homo sapiens
Length	423 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.45
monocyte count · score 0.20
electrocardiography · score 0.09
TPE interval measurement · score 0.08
P wave duration · score 0.08
PR interval · score 0.07
T wave morphology measurement · score 0.06
body mass index · score 0.05
age at menarche · score 0.05
serum urea measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BZE1-F1	alphafold	PREDICTED	89.08	—

Amino-acid sequence (423 residues)

MALASGPARR ALAGSGQLGL GGFGAPRRGA YEWGVRSTRK SEPPPLDRVY EIPGLEPITF AGKMHFVPWL ARPIFPPWDR GYKDPRFYRS PPLHEHPLYK DQACYIFHHR CRLLEGVKQA LWLTKTKLIE GLPEKVLSLV DDPRNHIENQ DECVLNVISH ARLWQTTEEI PKRETYCPVI VDNLIQLCKS QILKHPSLAR RICVQNSTFS ATWNRESLLL QVRGSGGARL STKDPLPTIA SREEIEATKN HVLETFYPIS PIIDLHECNI YDVKNDTGFQ EGYPYPYPHT LYLLDKANLR PHRLQPDQLR AKMILFAFGS ALAQARLLYG NDAKVLEQPV VVQSVGTDGR VFHFLVFQLN TTDLDCNEGV KNLAWVDSDQ LLYQHFWCLP VIKKRVVVEP VGPVGFKPET FRKFLALYLH GAA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards