Group IIF secretory phospholipase A2 (PLA2G2F)

About Group IIF secretory phospholipase A2

Group IIF secretory phospholipase A2 (PLA2G2F) is a protein from Homo sapiens identified by UniProt accession Q9BZM2, 168 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Group IIF secretory phospholipase A2
UniProt accession	Q9BZM2
Gene	PLA2G2F
Organism	Homo sapiens
Length	168 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.18
breast adenocarcinoma · score 0.18
cutaneous melanoma · score 0.10
psoriasis · score 0.04
telomere length · score 0.03
polyunsaturated fatty acid measurement · score 0.03
neoplasm · score 0.02
breast carcinoma · score 0.02
non-small cell lung carcinoma · score 0.02
urinary bladder carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BZM2-F1	alphafold	PREDICTED	89.01	—

Amino-acid sequence (168 residues)

MKKFFTVAIL AGSVLSTAHG SLLNLKAMVE AVTGRSAILS FVGYGCYCGL GGRGQPKDEV DWCCHAHDCC YQELFDQGCH PYVDHYDHTI ENNTEIVCSD LNKTECDKQT CMCDKNMVLC LMNQTYREEY RGFLNVYCQG PTPNCSIYEP PPEEVTCSHQ SPAPPAPP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards