About RING finger protein unkempt homolog
RING finger protein unkempt homolog (UNK) is a protein
from Homo sapiens identified by UniProt accession
Q9C0B0, 810 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | RING finger protein unkempt homolog |
|---|
| UniProt accession | Q9C0B0 |
|---|
| Gene | UNK |
|---|
| Organism | Homo sapiens |
|---|
| Length | 810 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.25
- eosinophil count · score 0.22
- bilirubin measurement · score 0.19
- serum alanine aminotransferase measurement · score 0.18
- apolipoprotein A 1 measurement · score 0.17
- Red cell distribution width · score 0.15
- low density lipoprotein cholesterol measurement · score 0.15
- asthma · score 0.13
- eosinophil percentage of leukocytes · score 0.12
- apolipoprotein B measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9C0B0-F1 | alphafold | PREDICTED | 64.87 | — |
Amino-acid sequence (810 residues)
MSKGPGPGGS AASSAPPAAT AQVLQAQPEK PQHYTYLKEF RTEQCPLFVQ HKCTQHRPYT CFHWHFVNQR RRRSIRRRDG TFNYSPDVYC TKYDEATGLC PEGDECPFLH RTTGDTERRY HLRYYKTGIC IHETDSKGNC TKNGLHCAFA HGPHDLRSPV YDIRELQAME ALQNGQTTVE GSIEGQSAGA ASHAMIEKIL SEEPRWQETA YVLGNYKTEP CKKPPRLCRQ GYACPYYHNS KDRRRSPRKH KYRSSPCPNV KHGDEWGDPG KCENGDACQY CHTRTEQQFH PEIYKSTKCN DMQQSGSCPR GPFCAFAHVE QPPLSDDLQP SSAVSSPTQP GPVLYMPSAA GDSVPVSPSS PHAPDLSALL CRNSSLGSPS NLCGSPPGSI RKPPNLEGIV FPGESGLAPG SYKKAPGFER EDQVGAEYLK NFKCQAKLKP HSLEPRSQEQ PLLQPKQDML GILPAGSPLT SSISSSITSS LAATPPSPVG TSSVPGMNAN ALPFYPTSDT VESVIESALD DLDLNEFGVA ALEKTFDNST VPHPGSITIG GSLLQSSAPV NIPGSLGSSA SFHSASPSPP VSLSSHFLQQ PQGHLSQSEN TFLGTSASHG SLGLNGMNSS IWEHFASGSF SPGTSPAFLS GPGAAELARL RQELDEANST IKQWEESWKQ AKQACDAWKK EAEEAGERAS AAGAECELAR EQRDALEVQV KKLQEELERL HAGPEPQALP AFSDLEALSL STLYSLQKQL RAHLEQVDKA VFHMQSVKCL KCQEQKRAVL PCQHAALCEL CAEGSECPIC QPGRAHTLQS
Explore RING finger protein unkempt homolog with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets