Barrier-to-autointegration factor-like protein (BANF2)

About Barrier-to-autointegration factor-like protein

Barrier-to-autointegration factor-like protein (BANF2) is a protein from Homo sapiens identified by UniProt accession Q9H503, 90 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	Barrier-to-autointegration factor-like protein
UniProt accession	Q9H503
Gene	BANF2
Organism	Homo sapiens
Length	90 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.33
uric acid measurement · score 0.32
body height · score 0.32
low density lipoprotein cholesterol measurement · score 0.32
bone density · score 0.32
urate measurement · score 0.32
balding measurement · score 0.29
apolipoprotein B measurement · score 0.27
eosinophil count · score 0.27
reticulocyte count · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H503-F1	alphafold	PREDICTED	95.97	—

Amino-acid sequence (90 residues)

MDNMSPRLRA FLSEPIGEKD VCWVDGISHE LAINLVTKGI NKAYILLGQF LLMHKNEAEF QRWLICCFGA TECEAQQTSH CLKEWCACFL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards