Ras-related and estrogen-regulated growth…

About Ras-related and estrogen-regulated growth inhibitor-like protein

Ras-related and estrogen-regulated growth inhibitor-like protein (RERGL) is a protein from Homo sapiens identified by UniProt accession Q9H628, 205 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Ras-related and estrogen-regulated growth inhibitor-like protein
UniProt accession	Q9H628
Gene	RERGL
Organism	Homo sapiens
Length	205 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.31
white matter microstructure measurement · score 0.29
adolescent idiopathic scoliosis · score 0.27
PHF-tau measurement · score 0.24
hypertension · score 0.20
body fat percentage · score 0.17
insomnia · score 0.14
total blood protein measurement · score 0.14
genetic disorder · score 0.12
prostate carcinoma · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H628-F1	alphafold	PREDICTED	76.86	—

Amino-acid sequence (205 residues)

MSNFLHLKYN EKSVSVTKAL TVRFLTKRFI GEYASNFESI YKKHLCLERK QLNLEIYDPC SQTQKAKFSL TSELHWADGF VIVYDISDRS SFAFAKALIY RIREPQTSHC KRAVESAVFL VGNKRDLCHV REVGWEEGQK LALENRCQFC ELSAAEQSLE VEMMFIRIIK DILINFKLKE KRRPSGSKSM AKLINNVFGK RRKSV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Ras-related and estrogen-regulated growth inhibitor-like protein (RERGL)