Damage-control phosphatase 1 (DCPH1)

About Damage-control phosphatase 1

Damage-control phosphatase 1 (DCPH1) is a protein from Homo sapiens identified by UniProt accession Q9H993, 441 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Damage-control phosphatase 1
UniProt accession	Q9H993
Gene	DCPH1
Organism	Homo sapiens
Length	441 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

age at menarche · score 0.25
electrocardiography · score 0.23
body height · score 0.22
Red cell distribution width · score 0.11
heel bone mineral density · score 0.07
myeloid white cell count · score 0.06
lean body mass · score 0.06
fat body mass · score 0.06
bone quantitative ultrasound measurement · score 0.05
lymphocyte count · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9H993-F1	alphafold	PREDICTED	94.85	—

Amino-acid sequence (441 residues)

MAVVPASLSG QDVGSFAYLT IKDRIPQILT KVIDTLHRHK SEFFEKHGEE GVEAEKKAIS LLSKLRNELQ TDKPFIPLVE KFVDTDIWNQ YLEYQQSLLN ESDGKSRWFY SPWLLVECYM YRRIHEAIIQ SPPIDYFDVF KESKEQNFYG SQESIIALCT HLQQLIRTIE DLDENQLKDE FFKLLQISLW GNKCDLSLSG GESSSQNTNV LNSLEDLKPF ILLNDMEHLW SLLSNCKKTR EKASATRVYI VLDNSGFELV TDLILADFLL SSELATEVHF YGKTIPWFVS DTTIHDFNWL IEQVKHSNHK WMSKCGADWE EYIKMGKWVY HNHIFWTLPH EYCAMPQVAP DLYAELQKAH LILFKGDLNY RKLTGDRKWE FSVPFHQALN GFHPAPLCTI RTLKAEIQVG LQPGQGEQLL ASEPSWWTTG KYGIFQYDGP L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards