Histone deacetylase complex subunit SAP30L (SAP30L)

About Histone deacetylase complex subunit SAP30L

Histone deacetylase complex subunit SAP30L (SAP30L) is a protein from Homo sapiens identified by UniProt accession Q9HAJ7, 183 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Histone deacetylase complex subunit SAP30L
UniProt accession	Q9HAJ7
Gene	SAP30L
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

Alzheimer disease · score 0.24
chin morphology measurement · score 0.14
left ventricular structural measurement · score 0.12
balding measurement · score 0.09
hair shape measurement · score 0.08
triglyceride measurement · score 0.07
electrocardiography · score 0.07
schizophrenia · score 0.04
QRS duration · score 0.04
QRS complex · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HAJ7-F1	alphafold	PREDICTED	75.42	—

Amino-acid sequence (183 residues)

MNGFSTEEDS REGPPAAPAA AAPGYGQSCC LIEDGERCVR PAGNASFSKR VQKSISQKKL KLDIDKSVRH LYICDFHKNF IQSVRNKRKR KTSDDGGDSP EHDTDIPEVD LFQLQVNTLR RYKRHYKLQT RPGFNKAQLA ETVSRHFRNI PVNEKETLAY FIYMVKSNKS RLDQKSEGGK QLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards