Transcription and mRNA export factor ENY2 (ENY2)

About Transcription and mRNA export factor ENY2

Transcription and mRNA export factor ENY2 (ENY2) is a protein from Homo sapiens identified by UniProt accession Q9NPA8, 101 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Transcription and mRNA export factor ENY2
UniProt accession	Q9NPA8
Gene	ENY2
Organism	Homo sapiens
Length	101 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.56
lysosomal storage disease · score 0.27
grip strength measurement · score 0.14
hepatocellular carcinoma · score 0.07
self reported educational attainment · score 0.06
intelligence · score 0.06
schizophrenia · score 0.06
cancer · score 0.04
platelet crit · score 0.04
infection · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPA8-F1	alphafold	PREDICTED	93.56	—

Amino-acid sequence (101 residues)

MVVSKMNKDA QMRAAINQKL IETGERERLK ELLRAKLIEC GWKDQLKAHC KEVIKEKGLE HVTVDDLVAE ITPKGRALVP DSVKKELLQR IRTFLAQHAS L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards