About Interleukin-26
Interleukin-26 (IL26) is a protein
from Homo sapiens identified by UniProt accession
Q9NPH9, 171 residues long.
MolForge cross-references it against 0 known binders and
182 disease associations.
Target properties
| Protein name | Interleukin-26 |
|---|
| UniProt accession | Q9NPH9 |
|---|
| Gene | IL26 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 171 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (182)
Diseases linked to this target (Open Targets).
- mosquito bite reaction itch intensity measurement · score 0.18
- mosquito bite reaction size measurement · score 0.18
- eosinophil count · score 0.16
- inflammatory bowel disease · score 0.13
- neurofibrillary tangles measurement · score 0.12
- Crohn's disease · score 0.11
- Rheumatoid arthritis · score 0.10
- antisocial behaviour measurement · score 0.10
- attention deficit hyperactivity disorder · score 0.10
- smoking status measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NPH9-F1 | alphafold | PREDICTED | 85.17 | — |
Amino-acid sequence (171 residues)
MLVNFILRCG LLLVTLSLAI AKHKQSSFTK SCYPRGTLSQ AVDALYIKAA WLKATIPEDR IKNIRLLKKK TKKQFMKNCQ FQEQLLSFFM EDVFGQLQLQ GCKKIRFVED FHSLRQKLSH CISCASSARE MKSITRMKRI FYRIGNKGIY KAISELDILL SWIKKLLESS Q
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