SLC2A4 regulator (SLC2A4RG)

About SLC2A4 regulator

SLC2A4 regulator (SLC2A4RG) is a protein from Homo sapiens identified by UniProt accession Q9NR83, 387 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.

Target properties

Protein name	SLC2A4 regulator
UniProt accession	Q9NR83
Gene	SLC2A4RG
Organism	Homo sapiens
Length	387 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (87)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.29
prostate carcinoma · score 0.27
apolipoprotein A 1 measurement · score 0.19
multiple sclerosis · score 0.19
body height · score 0.18
sex hormone-binding globulin measurement · score 0.14
serum gamma-glutamyl transferase measurement · score 0.12
high density lipoprotein cholesterol measurement · score 0.12
serum alanine aminotransferase measurement · score 0.11
prostate cancer · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NR83-F1	alphafold	PREDICTED	59.39	—

Amino-acid sequence (387 residues)

MERPPPRAAG RDPSALRAEA PWLRAEGPGP RAAPVTVPTP PQGSSVGGGF AGLEFARPQE SEPRASDLGA PRTWTGAAAG PRTPSAHIPV PAQRATPGKA RLDEVMAAAA LTSLSTSPLL LGAPVAAFSP EPGLEPWKEA LVRPPGSYSS SSNSGDWGWD LASDQSSPST PSPPLPPEAA HFLFGEPTLR KRKSPAQVMF QCLWKSCGKV LSTASAMQRH IRLVHLGRQA EPEQSDGEED FYYTELDVGV DTLTDGLSSL TPVSPTASMP PAFPRLELPE LLEPPALPSP LRPPAPPLPP PPVLSTVANP QSCHSDRVYQ GCLTPARLEP QPTEVGACPP ALSSRIGVTL RKPRGDAKKC RKVYGMERRD LWCTACRWKK ACQRFLD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards