COX assembly mitochondrial protein 2 homolog (CMC2)

About COX assembly mitochondrial protein 2 homolog

COX assembly mitochondrial protein 2 homolog (CMC2) is a protein from Homo sapiens identified by UniProt accession Q9NRP2, 79 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	COX assembly mitochondrial protein 2 homolog
UniProt accession	Q9NRP2
Gene	CMC2
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (39)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.40
heel bone mineral density · score 0.24
blood urea nitrogen measurement · score 0.23
serum urea measurement · score 0.15
cystatin C measurement · score 0.13
mean corpuscular volume · score 0.12
mean reticulocyte volume · score 0.10
mosaic loss of chromosome Y measurement · score 0.09
mean corpuscular hemoglobin · score 0.06
glycine measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NRP2-F1	alphafold	PREDICTED	91.59	—

Amino-acid sequence (79 residues)

MHPDLSPHLH TEECNVLINL LKECHKNHNI LKFFGYCNDV DRELRKCLKN EYVENRTKSR EHGIAMRKKL FNPPEESEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards