Obg-like ATPase 1 (OLA1)

About Obg-like ATPase 1

Obg-like ATPase 1 (OLA1) is a protein from Homo sapiens identified by UniProt accession Q9NTK5, 396 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

Target properties

Protein name	Obg-like ATPase 1
UniProt accession	Q9NTK5
Gene	OLA1
Organism	Homo sapiens
Length	396 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (90)

Diseases linked to this target (Open Targets).

body mass index · score 0.40
reaction time measurement · score 0.37
digit length ratio · score 0.37
systolic blood pressure · score 0.35
blood protein measurement · score 0.34
diet measurement · score 0.33
body fat percentage · score 0.32
age at first facial hair · score 0.31
brain measurement · score 0.29
smoking behavior · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NTK5-F1	alphafold	PREDICTED	88.22	—

Amino-acid sequence (396 residues)

MPPKKGGDGI KPPPIIGRFG TSLKIGIVGL PNVGKSTFFN VLTNSQASAE NFPFCTIDPN ESRVPVPDER FDFLCQYHKP ASKIPAFLNV VDIAGLVKGA HNGQGLGNAF LSHISACDGI FHLTRAFEDD DITHVEGSVD PIRDIEIIHE ELQLKDEEMI GPIIDKLEKV AVRGGDKKLK PEYDIMCKVK SWVIDQKKPV RFYHDWNDKE IEVLNKHLFL TSKPMVYLVN LSEKDYIRKK NKWLIKIKEW VDKYDPGALV IPFSGALELK LQELSAEERQ KYLEANMTQS ALPKIIKAGF AALQLEYFFT AGPDEVRAWT IRKGTKAPQA AGKIHTDFEK GFIMAEVMKY EDFKEEGSEN AVKAAGKYRQ QGRNYIVEDG DIIFFKFNTP QQPKKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards