Copper homeostasis protein cutC homolog (CUTC)

About Copper homeostasis protein cutC homolog

Copper homeostasis protein cutC homolog (CUTC) is a protein from Homo sapiens identified by UniProt accession Q9NTM9, 273 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Copper homeostasis protein cutC homolog
UniProt accession	Q9NTM9
Gene	CUTC
Organism	Homo sapiens
Length	273 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

Leigh syndrome · score 0.19
leigh syndrome due to mitochondrial complex iv deficiency · score 0.12
fatal infantile encephalocardiomyopathy · score 0.12
mitochondrial complex IV deficiency, nuclear type 22 · score 0.12
platelet crit · score 0.08
aspartate aminotransferase measurement · score 0.08
diverticulitis · score 0.06
mean corpuscular volume · score 0.06
metabolite measurement · score 0.05
serum alanine aminotransferase measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NTM9-F1	alphafold	PREDICTED	91.44	—

Amino-acid sequence (273 residues)

MKRQGASSER KRARIPSGKA GAANGFLMEV CVDSVESAVN AERGGADRIE LCSGLSEGGT TPSMGVLQVV KQSVQIPVFV MIRPRGGDFL YSDREIEVMK ADIRLAKLYG ADGLVFGALT EDGHIDKELC MSLMAICRPL PVTFHRAFDM VHDPMAALET LLTLGFERVL TSGCDSSALE GLPLIKRLIE QAKGRIVVMP GGGITDRNLQ RILEGSGATE FHCSARSTRD SGMKFRNSSV AMGASLSCSE YSLKVTDVTK VRTLNAIAKN ILV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards