About Cation channel sperm-associated auxiliary subunit zeta
Cation channel sperm-associated auxiliary subunit zeta (CATSPERZ) is a protein
from Homo sapiens identified by UniProt accession
Q9NTU4, 200 residues long.
MolForge cross-references it against 0 known binders and
102 disease associations.
Target properties
| Protein name | Cation channel sperm-associated auxiliary subunit zeta |
|---|
| UniProt accession | Q9NTU4 |
|---|
| Gene | CATSPERZ |
|---|
| Organism | Homo sapiens |
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| Length | 200 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (102)
Diseases linked to this target (Open Targets).
- body mass index · score 0.22
- body fat percentage · score 0.20
- lean body mass · score 0.14
- fat body mass · score 0.12
- body height · score 0.11
- body weight · score 0.11
- platelet count · score 0.08
- azoospermia · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.08
- spermatogenic failure 3 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NTU4-F1 | alphafold | PREDICTED | 62.17 | — |
Amino-acid sequence (200 residues)
MEEKPSKVSL KSSDRQGSDE ESVHSDTRDL WTTTTLSQAQ LNMPLSEVCE GFDEEGRNIS KTRGWHSPGR GSLDEGYKAS HKPEELDEHA LVELELHRGS SMEINLGEKD TASQIEAEKS SSMSSLNIAK HMPHRAYWAE QQSRLPLPLM ELMENEALEI LTKALRSYQL GIGRDHFLTK ELQRYIEGLK KRRSKRLYVN
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