Cerebellin-4 (CBLN4)

Homo sapiens — UniProt Q9NTU7

Gene: CBLN4Homo sapiensSwissProt reviewed

About Cerebellin-4

Cerebellin-4 (CBLN4) is a protein from Homo sapiens identified by UniProt accession Q9NTU7, 201 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein nameCerebellin-4
UniProt accessionQ9NTU7
GeneCBLN4
OrganismHomo sapiens
Length201 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (47)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.32
  • body weight · score 0.31
  • neurodegenerative disease · score 0.27
  • lean body mass · score 0.24
  • smoking initiation · score 0.23
  • blood protein measurement · score 0.23
  • protein measurement · score 0.22
  • smoking status measurement · score 0.19
  • appendicular lean mass · score 0.17
  • body height · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NTU7-F1alphafoldPREDICTED78.89—

Amino-acid sequence (201 residues)

MGSGRRALSA VPAVLLVLTL PGLPVWAQND TEPIVLEGKC LVVCDSNPAT DSKGSSSSPL GISVRAANSK VAFSAVRSTN HEPSEMSNKT RIIYFDQILV NVGNFFTLES VFVAPRKGIY SFSFHVIKVY QSQTIQVNLM LNGKPVISAF AGDKDVTREA ATNGVLLYLD KEDKVYLKLE KGNLVGGWQY STFSGFLVFP L

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Quick facts

UniProtQ9NTU7
GeneCBLN4
OrganismHomo sapiens
Length201
Binders0
Diseases47
View on UniProt