About WD repeat-containing protein 70
WD repeat-containing protein 70 (WDR70) is a protein
from Homo sapiens identified by UniProt accession
Q9NW82, 654 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | WD repeat-containing protein 70 |
|---|
| UniProt accession | Q9NW82 |
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| Gene | WDR70 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 654 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.31
- neurodegenerative disease · score 0.27
- appendicular lean mass · score 0.22
- body height · score 0.19
- diverticulitis · score 0.11
- type 1 diabetes mellitus · score 0.10
- diverticular disease · score 0.06
- alkaline phosphatase measurement · score 0.04
- diet measurement · score 0.03
- urate measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NW82-F1 | alphafold | PREDICTED | 78.04 | — |
Amino-acid sequence (654 residues)
MERSGPSEVT GSDASGPDPQ LAVTMGFTGF GKKARTFDLE AMFEQTRRTA VERSRKTLEA REKEEEMNRE KELRRQNEDI EPTSSRSNVV RDCSKSSSRD TSSSESEQSS DSSDDELIGP PLPPKMVGKP VNFMEEDILG PLPPPLNEEE EEAEEEEEEE EEEENPVHKI PDSHEITLKH GTKTVSALGL DPSGARLVTG GYDYDVKFWD FAGMDASFKA FRSLQPCECH QIKSLQYSNT GDMILVVSGS SQAKVIDRDG FEVMECIKGD QYIVDMANTK GHTAMLHTGS WHPKIKGEFM TCSNDATVRT WEVENPKKQK SVFKPRTMQG KKVIPTTCTY SRDGNLIAAA CQNGSIQIWD RNLTVHPKFH YKQAHDSGTD TSCVTFSYDG NVLASRGGDD SLKLWDIRQF NKPLFSASGL PTMFPMTDCC FSPDDKLIVT GTSIQRGCGS GKLVFFERRT FQRVYEIDIT DASVVRCLWH PKLNQIMVGT GNGLAKVYYD PNKSQRGAKL CVVKTQRKAK QAETLTQDYI ITPHALPMFR EPRQRSTRKQ LEKDRLDPLK SHKPEPPVAG PGRGGRVGTH GGTLSSYIVK NIALDKTDDS NPREAILRHA KAAEDSPYWV SPAYSKTQPK TMFAQVESDD EEAKNEPEWK KRKI
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