Protein FAM118A (FAM118A)

About Protein FAM118A

Protein FAM118A (FAM118A) is a protein from Homo sapiens identified by UniProt accession Q9NWS6, 357 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.

Target properties

Protein name	Protein FAM118A
UniProt accession	Q9NWS6
Gene	FAM118A
Organism	Homo sapiens
Length	357 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (131)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
puberty onset measurement · score 0.34
heel bone mineral density · score 0.31
cortical surface area measurement · score 0.30
dentures · score 0.29
balding measurement · score 0.29
hair shape measurement · score 0.28
chronotype measurement · score 0.26
pulse pressure measurement · score 0.25
brain measurement · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NWS6-F1	alphafold	PREDICTED	83.19	—

Amino-acid sequence (357 residues)

MDSVEKTTNR SEQKSRKFLK SLIRKQPQEL LLVIGTGVSA AVAPGIPALC SWRSCIEAVI EAAEQLEVLH PGDVAEFRRK VTKDRDLLVV AHDLIRKMSP RTGDAKPSFF QDCLMEVFDD LEQHIRSPVV LQSILSLMDR GAMVLTTNYD NLLEAFGRRQ NKPMESLDLK DKTKVLEWAR GHMKYGVLHI HGLYTDPCGV VLDPSGYKDV TQDAEVMEVL QNLYRTKSFL FVGCGETLRD QIFQALFLYS VPNKVDLEHY MLVLKENEDH FFKHQADMLL HGIKVVSYGD CFDHFPGYVQ DLATQICKQQ SPDADRVDST TLLGNACQDC AKRKLEENGI EVSKKRTQSD TDDAGGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards