About Zinc finger and SCAN domain-containing protein 32
Zinc finger and SCAN domain-containing protein 32 (ZSCAN32) is a protein
from Homo sapiens identified by UniProt accession
Q9NX65, 697 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 32 |
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| UniProt accession | Q9NX65 |
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| Gene | ZSCAN32 |
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| Organism | Homo sapiens |
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| Length | 697 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- IGF-1 measurement · score 0.04
- insulin like growth factor measurement · score 0.03
- diastolic blood pressure · score 0.03
- vital capacity · score 0.02
- serum alanine aminotransferase measurement · score 0.02
- neoplasm · score 0.00
- Obesity · score 0.00
- lung adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NX65-F1 | alphafold | PREDICTED | 54.06 | — |
Amino-acid sequence (697 residues)
MMAAVKSTEA HPSSNKDPTQ GQKSALQGNS PDSEASRQRF RQFCYQEVTG PHEAFSKLWE LCCQWLRPKT HSKEEILELL VLEQFLTILP EEIQTWVREQ HPENGEEAVA LVEDVQRAPG QQVLDSEKDL KVLMKEMAPL GATRESLRSQ WKQEVQPEEP TFKGSQSSHQ RPGEQSEAWL APQAPRNLPQ NTGLHDQETG AVVWTAGSQG PAMRDNRAVS LCQQEWMCPG PAQRALYRGA TQRKDSHVSL ATGVPWGYEE TKTLLAILSS SQFYGKLQTC QQNSQIYRAM AEGLWEQGFL RTPEQCRTKF KSLQLSYRKV RRGRVPEPCI FYEEMNALSG SWASAPPMAS DAVPGQEGSD IEAGELNHQN GEPTEVEDGT VDGADRDEKD FRNPGQEVRK LDLPVLFPNR LGFEFKNEIK KENLKWDDSE EVEINKALQR KSRGVYWHSE LQKGLESEPT SRRQCRNSPG ESEEKTPSQE KMSHQSFCAR DKACTHILCG KNCSQSVHSP HKPALKLEKV SQCPECGKTF SRSSYLVRHQ RIHTGEKPHK CSECGKGFSE RSNLTAHLRT HTGERPYQCG QCGKSFNQSS SLIVHQRTHT GEKPYQCIVC GKRFNNSSQF SAHRRIHTGE SPYKCAVCGK IFNNSSHFSA HRKTHTGEKP YRCSHCERGF TKNSALTRHQ TVHMKAVLSS QEGRDAL
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