Protein Mis18-alpha (MIS18A)

About Protein Mis18-alpha

Protein Mis18-alpha (MIS18A) is a protein from Homo sapiens identified by UniProt accession Q9NYP9, 233 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Protein Mis18-alpha
UniProt accession	Q9NYP9
Gene	MIS18A
Organism	Homo sapiens
Length	233 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.07
neoplasm · score 0.05
motor neuron disease · score 0.05
pancreatic adenocarcinoma · score 0.02
cancer · score 0.02
psoriasis · score 0.01
Miyoshi myopathy · score 0.01
vulvar intraepithelial neoplasia · score 0.01
Obesity · score 0.01
infect · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NYP9-F1	alphafold	PREDICTED	79.14	—

Amino-acid sequence (233 residues)

MAGVRSLRCS RGCAGGCECG DKGKCSDSSL LGKRLSEDSS RHQLLQKWAS MWSSMSEDAS VADMERAQLE EEAAAAEERP LVFLCSGCRR PLGDSLSWVA SQEDTNCILL RCVSCNVSVD KEQKLSKREK ENGCVLETLC CAGCSLNLGY VYRCTPKNLD YKRDLFCLSV EAIESYVLGS SEKQIVSEDK ELFNLESRVE IEKSLTQMED VLKALQMKLW EAESKLSFAT CKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards