About Interleukin-17C
Interleukin-17C (IL17C) is a protein
from Homo sapiens identified by UniProt accession
Q9P0M4, 197 residues long.
MolForge cross-references it against 0 known binders and
180 disease associations.
Target properties
| Protein name | Interleukin-17C |
| UniProt accession | Q9P0M4 |
| Gene | IL17C |
| Organism | Homo sapiens |
| Length | 197 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (180)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- mean corpuscular volume · score 0.14
- mean corpuscular hemoglobin concentration · score 0.12
- neoplasm · score 0.09
- liver dysplastic nodule · score 0.07
- psoriasis · score 0.05
- major depressive disorder · score 0.05
- aspartate aminotransferase measurement · score 0.05
- acne inversa, familial, 3 · score 0.05
- hidradenitis suppurativa · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9P0M4-F1 | alphafold | PREDICTED | 82.07 | — |
Amino-acid sequence (197 residues)
MTLLPGLLFL TWLHTCLAHH DPSLRGHPHS HGTPHCYSAE ELPLGQAPPH LLARGAKWGQ ALPVALVSSL EAASHRGRHE RPSATTQCPV LRPEEVLEAD THQRSISPWR YRVDTDEDRY PQKLAFAECL CRGCIDARTG RETAALNSVR LLQSLLVLRR RPCSRDGSGL PTPGAFAFHT EFIHVPVGCT CVLPRSV
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