About Zinc finger protein 319
Zinc finger protein 319 (ZNF319) is a protein
from Homo sapiens identified by UniProt accession
Q9P2F9, 582 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Zinc finger protein 319 |
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| UniProt accession | Q9P2F9 |
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| Gene | ZNF319 |
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| Organism | Homo sapiens |
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| Length | 582 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.25
- Hematuria · score 0.22
- eosinophil count · score 0.17
- eosinophil percentage of leukocytes · score 0.15
- chronic obstructive pulmonary disease · score 0.14
- serum gamma-glutamyl transferase measurement · score 0.06
- serum alanine aminotransferase measurement · score 0.06
- body fat percentage · score 0.04
- sex hormone-binding globulin measurement · score 0.03
- low density lipoprotein triglyceride measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2F9-F1 | alphafold | PREDICTED | 64.00 | — |
Amino-acid sequence (582 residues)
MSESWQQPPQ TQPQQPQPPQ PQHHAEPPPA LAEHTLPPGT AENPLGCAVY GILLQPDPGL QPPQHAPLQA AGEPGPKCGV CGHDLAHLSS PHEHQCLAGH DRSFQCTQCL KIFHQATDLL EHQCVQAEQK PFVCGVCKMG FSLLTSLAQH HSSHSGLVKC SICEKTYKPA EAAEPATTAA PSLPAAPAPS TVTPAEQADK PYSCPICQKP FKHLSELSRH ERIHTGEKPY KCTLCDKSFS QSSHLVHHKR THSSERPYKC AVCEKTFKHR SHLVRHMYAH SGEHHLFRCN VCELHFKESS ELLQHPCTPS GERPFRCGEC QKAFKRPSDL RQHERTHSAE RPFKCDLCPM GFKQQYALMR HRRTHKTEEP FKCGLCEKGF GQPSHLLYHQ HVHTLETLFK CPVCQKGFDQ SAELLRHKCL PGAAERPFKC PVCNKAYKRA SALQKHQLAH CAAAEKPLRC TLCERRFFSS SEFVQHRCDP AREKPLKCPD CEKRFKYASD LQRHRRVHTG EKPYKCPNCD KAFKQREHLN KHQGVHAREQ QFKCVWCGER FLDVALLQEH SAQHSAAAAA AEGAYQVAAC LP
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