Vacuolar protein sorting-associated protein 29 (VPS29)

About Vacuolar protein sorting-associated protein 29

Vacuolar protein sorting-associated protein 29 (VPS29) is a protein from Homo sapiens identified by UniProt accession Q9UBQ0, 182 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Vacuolar protein sorting-associated protein 29
UniProt accession	Q9UBQ0
Gene	VPS29
Organism	Homo sapiens
Length	182 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.55
lysosomal storage disease · score 0.37
genetic disorder · score 0.12
alcohol drinking · score 0.09
fat body mass · score 0.08
body fat percentage · score 0.08
body mass index · score 0.08
lean body mass · score 0.07
calcium measurement · score 0.07
electrocardiography · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBQ0-F1	alphafold	PREDICTED	96.60	—

Amino-acid sequence (182 residues)

MLVLVLGDLH IPHRCNSLPA KFKKLLVPGK IQHILCTGNL CTKESYDYLK TLAGDVHIVR GDFDENLNYP EQKVVTVGQF KIGLIHGHQV IPWGDMASLA LLQRQFDVDI LISGHTHKFE AFEHENKFYI NPGSATGAYN ALETNIIPSF VLMDIQASTV VTYVYQLIGD DVKVERIEYK KP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards