Lipid transferase CIDEB (CIDEB)

About Lipid transferase CIDEB

Lipid transferase CIDEB (CIDEB) is a protein from Homo sapiens identified by UniProt accession Q9UHD4, 219 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Lipid transferase CIDEB
UniProt accession	Q9UHD4
Gene	CIDEB
Organism	Homo sapiens
Length	219 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

nonpapillary renal cell carcinoma · score 0.07
language impairment · score 0.06
obesity due to melanocortin 4 receptor deficiency · score 0.05
CIDEC-related familial partial lipodystrophy · score 0.05
AKT2-related familial partial lipodystrophy · score 0.04
Hyperlipoproteinemia type 1 · score 0.04
LIPE-related familial partial lipodystrophy · score 0.04
Generalized congenital lipodystrophy with myopathy · score 0.04
Obesity · score 0.04
Hepatic steatosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UHD4-F1	alphafold	PREDICTED	73.55	—

Amino-acid sequence (219 residues)

MEYLSALNPS DLLRSVSNIS SEFGRRVWTS APPPQRPFRV CDHKRTIRKG LTAATRQELL AKALETLLLN GVLTLVLEED GTAVDSEDFF QLLEDDTCLM VLQSGQSWSP TRSGVLSYGL GRERPKHSKD IARFTFDVYK QNPRDLFGSL NVKATFYGLY SMSCDFQGLG PKKVLRELLR WTSTLLQGLG HMLLGISSTL RHAVEGAEQW QQKGRLHSY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards