About C-type lectin domain family 2 member D
C-type lectin domain family 2 member D (CLEC2D) is a protein
from Homo sapiens identified by UniProt accession
Q9UHP7, 191 residues long.
MolForge cross-references it against 0 known binders and
216 disease associations.
Target properties
| Protein name | C-type lectin domain family 2 member D |
|---|
| UniProt accession | Q9UHP7 |
|---|
| Gene | CLEC2D |
|---|
| Organism | Homo sapiens |
|---|
| Length | 191 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (216)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.34
- type 1 diabetes mellitus · score 0.33
- leukocyte count · score 0.31
- autoimmune thyroid disease · score 0.30
- lymphocyte count · score 0.26
- sleep duration · score 0.24
- high density lipoprotein cholesterol measurement · score 0.24
- thyroid disease · score 0.19
- basophil count · score 0.15
- drug use measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UHP7-F1 | alphafold | PREDICTED | 86.07 | — |
Amino-acid sequence (191 residues)
MHDSNNVEKD ITPSELPANP GCLHSKEHSI KATLIWRLFF LIMFLTIIVC GMVAALSAIR ANCHQEPSVC LQAACPESWI GFQRKCFYFS DDTKNWTSSQ RFCDSQDADL AQVESFQELN FLLRYKGPSD HWIGLSREQG QPWKWINGTE WTRQFPILGA GECAYLNDKG ASSARHYTER KWICSKSDIH V
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