About SLAM family member 5
SLAM family member 5 (CD84) is a protein
from Homo sapiens identified by UniProt accession
Q9UIB8, 345 residues long.
MolForge cross-references it against 0 known binders and
183 disease associations.
Target properties
| Protein name | SLAM family member 5 |
|---|
| UniProt accession | Q9UIB8 |
|---|
| Gene | CD84 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 345 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (183)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.26
- leukocyte count · score 0.26
- monocyte count · score 0.22
- CINCA syndrome · score 0.18
- breast adenocarcinoma · score 0.18
- eosinophil count · score 0.12
- head and neck squamous cell carcinoma · score 0.11
- eosinophil percentage of leukocytes · score 0.10
- PHF-tau measurement · score 0.08
- Miyoshi myopathy · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UIB8-F1 | alphafold | PREDICTED | 74.57 | — |
Amino-acid sequence (345 residues)
MAQHHLWILL LCLQTWPEAA GKDSEIFTVN GILGESVTFP VNIQEPRQVK IIAWTSKTSV AYVTPGDSET APVVTVTHRN YYERIHALGP NYNLVISDLR MEDAGDYKAD INTQADPYTT TKRYNLQIYR RLGKPKITQS LMASVNSTCN VTLTCSVEKE EKNVTYNWSP LGEEGNVLQI FQTPEDQELT YTCTAQNPVS NNSDSISARQ LCADIAMGFR THHTGLLSVL AMFFLLVLIL SSVFLFRLFK RRQGRIFPEG SCLNTFTKNP YAASKKTIYT YIMASRNTQP AESRIYDEIL QSKVLPSKEE PVNTVYSEVQ FADKMGKAST QDSKPPGTSS YEIVI
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