Psoriasis susceptibility 1 candidate gene 2 protein…

About Psoriasis susceptibility 1 candidate gene 2 protein

Psoriasis susceptibility 1 candidate gene 2 protein (PSORS1C2) is a protein from Homo sapiens identified by UniProt accession Q9UIG4, 136 residues long. MolForge cross-references it against 0 known binders and 140 disease associations.

Target properties

Protein name	Psoriasis susceptibility 1 candidate gene 2 protein
UniProt accession	Q9UIG4
Gene	PSORS1C2
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (140)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.25
uric acid measurement · score 0.24
unipolar depression · score 0.24
anti-drug antibody measurement · score 0.11
response to interferon-beta · score 0.11
non-Hodgkins lymphoma · score 0.10
head and neck squamous cell carcinoma · score 0.10
body height · score 0.10
systemic scleroderma · score 0.10
lymphocyte count · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UIG4-F1	alphafold	PREDICTED	70.71	—

Amino-acid sequence (136 residues)

MILNWKLLGI LVLCLHTRGI SGSEGHPSHP PAEDREEAGS PTLPQGPPVP GDPWPGAPPL FEDPPPTRPS RPWRDLPETG VWLPEPPRTD PPQPPRPDDP WPAGPQPPEN PWPPAPEVDN RPQEEPDLDP PREEYR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Psoriasis susceptibility 1 candidate gene 2 protein (PSORS1C2)