Psoriasis susceptibility 1 candidate gene 1 protein…

About Psoriasis susceptibility 1 candidate gene 1 protein

Psoriasis susceptibility 1 candidate gene 1 protein (PSORS1C1) is a protein from Homo sapiens identified by UniProt accession Q9UIG5, 152 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.

Target properties

Protein name	Psoriasis susceptibility 1 candidate gene 1 protein
UniProt accession	Q9UIG5
Gene	PSORS1C1
Organism	Homo sapiens
Length	152 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (103)

Diseases linked to this target (Open Targets).

peeling skin syndrome 1 · score 0.49
hypotrichosis 2 · score 0.43
ulcerative colitis · score 0.21
Behcet's syndrome · score 0.20
systemic lupus erythematosus · score 0.20
genetic disorder · score 0.19
hemoglobin measurement · score 0.18
schizophrenia · score 0.18
cutaneous lupus erythematosus · score 0.17
leukocyte count · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UIG5-F1	alphafold	PREDICTED	55.11	—

Amino-acid sequence (152 residues)

MTCTDQKSHS QRALGTQTPA LQGPQLLNTD PSSEETRPPH VNPDRLCHME PANHFWHAGD LQAMISKEFH LAATQDDCRK GRTQEDILVP SSHPELFASV LPMAPEEAAR LQQPQPLPPP SGIHLSASRT LAPTLLYSSP PSHSPFGLSS LI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Psoriasis susceptibility 1 candidate gene 1 protein (PSORS1C1)