About Biogenesis of lysosome-related organelles complex 1 subunit 6
Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC1S6) is a protein
from Homo sapiens identified by UniProt accession
Q9UL45, 172 residues long.
MolForge cross-references it against 0 known binders and
79 disease associations.
Target properties
| Protein name | Biogenesis of lysosome-related organelles complex 1 subunit 6 |
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| UniProt accession | Q9UL45 |
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| Gene | BLOC1S6 |
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| Organism | Homo sapiens |
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| Length | 172 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (79)
Diseases linked to this target (Open Targets).
- Hermansky-Pudlak syndrome 9 · score 0.77
- Hermansky-Pudlak syndrome · score 0.46
- Hermansky-Pudlak syndrome type 9 · score 0.37
- Hermansky-Pudlak syndrome type 7 · score 0.37
- genetic disorder · score 0.18
- health study participation · score 0.14
- autoinflammatory syndrome · score 0.12
- Griscelli syndrome type 3 · score 0.07
- Tietz syndrome · score 0.06
- oculocutaneous albinism type 3 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UL45-F1 | alphafold | PREDICTED | 82.79 | — |
Amino-acid sequence (172 residues)
MSVPGPSSPD GALTRPPYCL EAGEPTPGLS DTSPDEGLIE DLTIEDKAVE QLAEGLLSHY LPDLQRSKQA LQELTQNQVV LLDTLEQEIS KFKECHSMLD INALFAEAKH YHAKLVNIRK EMLMLHEKTS KLKKRALKLQ QKRQKEELER EQQREKEFER EKQLTARPAK RM
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