About Ras-related protein Rab-23
Ras-related protein Rab-23 (RAB23) is a protein
from Homo sapiens identified by UniProt accession
Q9ULC3, 237 residues long.
MolForge cross-references it against 0 known binders and
141 disease associations.
Target properties
| Protein name | Ras-related protein Rab-23 |
| UniProt accession | Q9ULC3 |
| Gene | RAB23 |
| Organism | Homo sapiens |
| Length | 237 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (141)
Diseases linked to this target (Open Targets).
- Carpenter syndrome · score 0.78
- RAB23-related Carpenter syndrome · score 0.66
- genetic disorder · score 0.41
- Polydactyly · score 0.37
- polydactyly · score 0.37
- coronary artery disease · score 0.26
- Myocardial Ischemia · score 0.18
- coronary atherosclerosis · score 0.18
- angina pectoris · score 0.13
- bladder exstrophy · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9ULC3-F1 | alphafold | PREDICTED | 79.57 | — |
Amino-acid sequence (237 residues)
MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSCSIP
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