Malignant T-cell-amplified sequence 1 (MCTS1)

About Malignant T-cell-amplified sequence 1

Malignant T-cell-amplified sequence 1 (MCTS1) is a protein from Homo sapiens identified by UniProt accession Q9ULC4, 181 residues long. MolForge cross-references it against 0 known binders and 150 disease associations.

Target properties

Protein name	Malignant T-cell-amplified sequence 1
UniProt accession	Q9ULC4
Gene	MCTS1
Organism	Homo sapiens
Length	181 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (150)

Diseases linked to this target (Open Targets).

genetic disorder · score 0.15
neoplasm · score 0.11
cancer · score 0.10
triple-negative breast cancer · score 0.10
breast cancer · score 0.08
hepatocellular carcinoma · score 0.08
lung adenocarcinoma · score 0.07
non-alcoholic steatohepatitis · score 0.06
Cataract-microcornea syndrome · score 0.06
microphthalmia · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9ULC4-F1	alphafold	PREDICTED	97.27	—

Amino-acid sequence (181 residues)

MFKKFDEKEN VSNCIQLKTS VIKGIKNQLI EQFPGIEPWL NQIMPKKDPV KIVRCHEHIE ILTVNGELLF FRQREGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG AKLYPAAVDT IVAIMAEGKQ HALCVGVMKM SAEDIEKVNK GIGIENIHYL NDGLWHMKTY K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards