Anaphase-promoting complex subunit 10 (ANAPC10)

About Anaphase-promoting complex subunit 10

Anaphase-promoting complex subunit 10 (ANAPC10) is a protein from Homo sapiens identified by UniProt accession Q9UM13, 185 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein name	Anaphase-promoting complex subunit 10
UniProt accession	Q9UM13
Gene	ANAPC10
Organism	Homo sapiens
Length	185 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (52)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.37
body height · score 0.35
reticulocyte count · score 0.33
appendicular lean mass · score 0.33
fat body mass · score 0.30
reticulocyte measurement · score 0.29
forced expiratory volume · score 0.28
lean body mass · score 0.28
monocyte count · score 0.27
mean reticulocyte volume · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UM13-F1	alphafold	PREDICTED	90.18	—

Amino-acid sequence (185 residues)

MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL ETYWQSDGSQ PHLVNIQFRR KTTVKTLCIY ADYKSDESYT PSKISVRVGN NFHNLQEIRQ LELVEPSGWI HVPLTDNHKK PTRTFMIQIA VLANHQNGRD THMRQIKIYT PVEESSIGKF PRCTTIDFMM YRSIR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards