About 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 (FUT9) is a protein
from Homo sapiens identified by UniProt accession
Q9Y231, 359 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 |
|---|
| UniProt accession | Q9Y231 |
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| Gene | FUT9 |
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| Organism | Homo sapiens |
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| Length | 359 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.47
- schizophrenia · score 0.38
- viral load · score 0.32
- intelligence · score 0.26
- neoplasm · score 0.09
- non-small cell lung carcinoma · score 0.05
- squamous cell carcinoma · score 0.04
- cancer · score 0.04
- gastric carcinoma · score 0.04
- Barrett's esophagus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y231-F1 | alphafold | PREDICTED | 90.51 | — |
Amino-acid sequence (359 residues)
MTSTSKGILR PFLIVCIILG CFMACLLIYI KPTNSWIFSP MESASSVLKM KNFFSTKTDY FNETTILVWV WPFGQTFDLT SCQAMFNIQG CHLTTDRSLY NKSHAVLIHH RDISWDLTNL PQQARPPFQK WIWMNLESPT HTPQKSGIEH LFNLTLTYRR DSDIQVPYGF LTVSTNPFVF EVPSKEKLVC WVVSNWNPEH ARVKYYNELS KSIEIHTYGQ AFGEYVNDKN LIPTISTCKF YLSFENSIHK DYITEKLYNA FLAGSVPVVL GPSRENYENY IPADSFIHVE DYNSPSELAK YLKEVDKNNK LYLSYFNWRK DFTVNLPRFW ESHACLACDH VKRHQEYKSV GNLEKWFWN
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