C-type lectin domain family 11 member A (CLEC11A)

About C-type lectin domain family 11 member A

C-type lectin domain family 11 member A (CLEC11A) is a protein from Homo sapiens identified by UniProt accession Q9Y240, 323 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	C-type lectin domain family 11 member A
UniProt accession	Q9Y240
Gene	CLEC11A
Organism	Homo sapiens
Length	323 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (110)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.32
body height · score 0.31
PHF-tau measurement · score 0.23
stem Cell Growth Factor beta measurement · score 0.19
lean body mass · score 0.15
BMI-adjusted waist circumference · score 0.09
gonorrhea · score 0.09
acute myeloid leukemia · score 0.07
gastrointestinal stromal tumor · score 0.06
neoplasm · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y240-F1	alphafold	PREDICTED	78.89	—

Amino-acid sequence (323 residues)

MQAAWLLGAL VVPQLLGFGH GARGAEREWE GGWGGAQEEE REREALMLKH LQEALGLPAG RGDENPAGTV EGKEDWEMEE DQGEEEEEEA TPTPSSGPSP SPTPEDIVTY ILGRLAGLDA GLHQLHVRLH ALDTRVVELT QGLRQLRNAA GDTRDAVQAL QEAQGRAERE HGRLEGCLKG LRLGHKCFLL SRDFEAQAAA QARCTARGGS LAQPADRQQM EALTRYLRAA LAPYNWPVWL GVHDRRAEGL YLFENGQRVS FFAWHRSPRP ELGAQPSASP HPLSPDQPNG GTLENCVAQA SDDGSWWDHD CQRRLYYVCE FPF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards