Transcription factor 19 (TCF19)

About Transcription factor 19

Transcription factor 19 (TCF19) is a protein from Homo sapiens identified by UniProt accession Q9Y242, 345 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

Target properties

Protein name	Transcription factor 19
UniProt accession	Q9Y242
Gene	TCF19
Organism	Homo sapiens
Length	345 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (90)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.28
type 2 diabetes mellitus · score 0.28
chronic hepatitis B virus infection · score 0.18
multiple myeloma · score 0.13
Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement · score 0.12
Stevens-Johnson syndrome · score 0.12
toxic epidermal necrolysis · score 0.12
Sensorineural hearing impairment · score 0.12
sensorineural hearing loss · score 0.12
ulcerative colitis · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y242-F1	alphafold	PREDICTED	62.59	—

Amino-acid sequence (345 residues)

MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR PMLPSQGAPQ RPLSTFSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK SLPVPAPPGE MGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE PCAAPCCCLP QEETVAWVQC DGCDVWFHVA CVGCSIQAAR EADFRCPGCR AGIQT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards