About Uronyl 2-sulfotransferase
Uronyl 2-sulfotransferase (UST) is a protein
from Homo sapiens identified by UniProt accession
Q9Y2C2, 406 residues long.
MolForge cross-references it against 0 known binders and
57 disease associations.
Target properties
| Protein name | Uronyl 2-sulfotransferase |
|---|
| UniProt accession | Q9Y2C2 |
|---|
| Gene | UST |
|---|
| Organism | Homo sapiens |
|---|
| Length | 406 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (57)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.42
- sodium measurement · score 0.42
- body height · score 0.42
- blood protein measurement · score 0.38
- cardiovascular disease · score 0.34
- sitting height measurement · score 0.32
- peak expiratory flow · score 0.27
- response to antidepressant · score 0.26
- drug use measurement · score 0.18
- atrial fibrillation · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y2C2-F1 | alphafold | PREDICTED | 79.08 | — |
Amino-acid sequence (406 residues)
MKKKQQHPGG GADPWPHGAP MGGAPPGLGS WKRRVPLLPF LRFSLRDYGF CMATLLVFCL GSLLYQLSGG PPRFLLDLRQ YLGNSTYLDD HGPPPSKVLP FPSQVVYNRV GKCGSRTVVL LLRILSEKHG FNLVTSDIHN KTRLTKNEQM ELIKNISTAE QPYLFTRHVH FLNFSRFGGD QPVYINIIRD PVNRFLSNYF FRRFGDWRGE QNHMIRTPSM RQEERYLDIN ECILENYPEC SNPRLFYIIP YFCGQHPRCR EPGEWALERA KLNVNENFLL VGILEELEDV LLLLERFLPH YFKGVLSIYK DPEHRKLGNM TVTVKKTVPS PEAVQILYQR MRYEYEFYHY VKEQFHLLKR KFGLKSHVSK PPLRPHFFIP TPLETEEPID DEEQDDEKWL EDIYKR
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