BTB/POZ domain-containing protein 3 (BTBD3)

About BTB/POZ domain-containing protein 3

BTB/POZ domain-containing protein 3 (BTBD3) is a protein from Homo sapiens identified by UniProt accession Q9Y2F9, 522 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	BTB/POZ domain-containing protein 3
UniProt accession	Q9Y2F9
Gene	BTBD3
Organism	Homo sapiens
Length	522 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

cigarettes per day measurement · score 0.36
health study participation · score 0.31
diastolic blood pressure · score 0.30
lifestyle measurement · score 0.30
hepatitis A virus infection · score 0.25
overall survival · score 0.20
PHF-tau measurement · score 0.20
platelet count · score 0.17
monocyte percentage of leukocytes · score 0.16
platelet crit · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y2F9-F1	alphafold	PREDICTED	83.52	—

Amino-acid sequence (522 residues)

MVDDKEKNMK CLTFFLMLPE TVKNRSKKSS KKANTSSSSS NSSKLPPVCY EIITLKTKKK KMAADIFPRK KPANSSSTSV QQYHQQNLSN NNLIPAPNWQ GLYPTIRERN AMMFNNDLMA DVHFVVGPPG GTQRLPGHKY VLAVGSSVFH AMFYGELAED KDEIRIPDVE PAAFLAMLKY IYCDEIDLAA DTVLATLYAA KKYIVPHLAR ACVNFLETSL SAKNACVLLS QSCLFEEPDL TQRCWEVIDA QAELALKSEG FCDIDFQTLE SILRRETLNA KEIVVFEAAL NWAEVECQRQ DLALSIENKR KVLGKALYLI RIPTMALDDF ANGAAQSGVL TLNETNDIFL WYTAAKKPEL QFVSKARKGL VPQRCHRFQS CAYRSNQWRY RGRCDSIQFA VDKRVFIAGF GLYGSSCGSA EYSAKIELKR QGVVLGQNLS KYFSDGSSNT FPVWFEYPVQ IEPDTFYTAS VILDGNELSY FGQEGMTEVQ CGKVTVQFQC SSDSTNGTGV QGGQIPELIF YA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards