About Zinc finger protein 835
Zinc finger protein 835 (ZNF835) is a protein
from Homo sapiens identified by UniProt accession
Q9Y2P0, 537 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger protein 835 |
| UniProt accession | Q9Y2P0 |
| Gene | ZNF835 |
| Organism | Homo sapiens |
| Length | 537 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- Down syndrome · score 0.05
- alkaline phosphatase measurement · score 0.03
- apolipoprotein B measurement · score 0.02
- low density lipoprotein cholesterol measurement · score 0.02
- psoriasis · score 0.01
- brucellosis · score 0.00
- endometrial carcinoma · score 0.00
- carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9Y2P0-F1 | alphafold | PREDICTED | 75.97 | — |
Amino-acid sequence (537 residues)
MEGLLSVALQ GAELEGNWKH EGQVEDLQEN QESCPEPEAV ACKGDPAGDS MQERDEFSRI PRTISSPAAT QASVPDDSSS RRCSAPGESP KERHPDSRQR ERGGGPKKPW KCGDCGKAFS YCSAFILHQR IHTGEKPFAC PECGKAFSQS VHLTLHQRTH TGEKPYACHE CGKAFSQGSY LASHWRTHTG EKPHRCADCG KAFTRVTHLT QHRRVHTGER PYACAQCAKA FRNRSSLIEH QRIHTGEKPY ECSACAKAFR FSSALIRHQR IHTEEKPYRC GQCAKAFAQI AHLTQHRRVH TGEKPYTCQD CGALFSQSAS LAEHRRIHTG EKPYACGQCA KAFTQVSHLT QHQRTHTGER PYPCHDCGKR FSNRSHLLQH RLVHTGERPY RCLQCGAAFS HVSSLIEHQK IHTGERPYKC GECGKAFSQG SSLALHQRTH TGERPYTCPE CGKAFSNRSY LIQHHIVHTG EKPYECSGCG KAFSFSSALI RHQRTHADSS GRLCPAPTPD STPGLSQGGE TCQQGCPGRN PRGPAED
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