START domain-containing protein 10 (STARD10)

About START domain-containing protein 10

START domain-containing protein 10 (STARD10) is a protein from Homo sapiens identified by UniProt accession Q9Y365, 291 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.

Target properties

Protein name	START domain-containing protein 10
UniProt accession	Q9Y365
Gene	STARD10
Organism	Homo sapiens
Length	291 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (101)

Diseases linked to this target (Open Targets).

C-reactive protein measurement · score 0.44
serum alanine aminotransferase measurement · score 0.38
platelet count · score 0.35
type 2 diabetes mellitus · score 0.34
diabetes mellitus · score 0.33
FEV/FVC ratio · score 0.33
glucose measurement · score 0.28
Drugs used in diabetes use measurement · score 0.25
mean platelet volume · score 0.25
fasting blood glucose measurement · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y365-F1	alphafold	PREDICTED	86.91	—

Amino-acid sequence (291 residues)

MEKLAASTEP QGPRPVLGRE SVQVPDDQDF RSFRSECEAE VGWNLTYSRA GVSVWVQAVE MDRTLHKIKC RMECCDVPAE TLYDVLHDIE YRKKWDSNVI ETFDIARLTV NADVGYYSWR CPKPLKNRDV ITLRSWLPMG ADYIIMNYSV KHPKYPPRKD LVRAVSIQTG YLIQSTGPKS CVITYLAQVD PKGSLPKWVV NKSSQFLAPK AMKKMYKACL KYPEWKQKHL PHFKPWLHPE QSPLPSLALS ELSVQHADSL ENIDESAVAE SREERMGGAG GEGSDDDTSL T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards