Transmembrane emp24 domain-containing protein 7…

About Transmembrane emp24 domain-containing protein 7

Transmembrane emp24 domain-containing protein 7 (TMED7) is a protein from Homo sapiens identified by UniProt accession Q9Y3B3, 224 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Transmembrane emp24 domain-containing protein 7
UniProt accession	Q9Y3B3
Gene	TMED7
Organism	Homo sapiens
Length	224 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

body height · score 0.31
forced expiratory volume · score 0.28
vital capacity · score 0.24
neurodegenerative disease · score 0.22
BMI-adjusted hip circumference · score 0.22
sitting height measurement · score 0.21
BMI-adjusted waist circumference · score 0.21
low density lipoprotein particle size measurement · score 0.04
neutrophil count · score 0.03
appendicular lean mass · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y3B3-F1	alphafold	PREDICTED	84.16	—

Amino-acid sequence (224 residues)

MPRPGSAQRW AAVAGRWGCR LLALLLLVPG PGGASEITFE LPDNAKQCFY EDIAQGTKCT LEFQVITGGH YDVDCRLEDP DGKVLYKEMK KQYDSFTFTA SKNGTYKFCF SNEFSTFTHK TVYFDFQVGE DPPLFPSENR VSALTQMESA CVSIHEALKS VIDYQTHFRL REAQGRSRAE DLNTRVAYWS VGEALILLVV SIGQVFLLKS FFSDKRTTTT RVGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Transmembrane emp24 domain-containing protein 7 (TMED7)